Epidermal changes in lichen planus.
作者： Herwig Ebner , Walter Gebhart
DOI: 10.1111/J.1600-0560.1976.TB00858.X
关键词:
摘要: Ultrastructural investigations in 15 patients with lichen planus (LP) revealed a multitude of epidermal changes. The most consistent findings were (1) multiplication, irregular folding or dislocation the basal lamina, (2) fragmentation degenerative changes keratinocytes, (3) formation numerous fibrillar Civatte bodies and, (4) presence dyskeratotic elements. In addition, mitotic figures keratinocytes and Langerhans cells observed. These support view that primary event LP represents an injury involving cells. Furthermore, replacement destroyed tissue seems to originate not only from margin lesions skin appendages but also unaffected within papule.
sci-hub.se 参考文章(23)
H. Ebner, W. Gebhart, Beitrag zur Histochemie und Ultrastruktur der sogenannten hyalinen bzw. kolloiden Körperchen Archiv f�r Dermatologische Forschung. ,vol. 242, pp. 153- 164 ,(1972) , 10.1007/BF00595563
H. Ebner, W. Gebhart, Die Ultrastruktur der Epidermis-Cutis-Grenze beim Lichen ruber planus Archiv f�r Dermatologische Forschung. ,vol. 245, pp. 285- 294 ,(1972) , 10.1007/BF00595146
G. Mahrle, H. Gartmann, C. E. Orfanos, Ulcerierender Lichen ruber der Füße Archiv f�r Dermatologische Forschung. ,vol. 243, pp. 292- 304 ,(1972) , 10.1007/BF00620410
I. Anton-Lamprecht, W. Tilgen, Zur Entstehung und Tonofibrillennatur der fibrillären Körper (sog. hyaline oder kolloide Körperchen) Archiv f�r Dermatologische Forschung. ,vol. 246, pp. 317- 327 ,(1973) , 10.1007/BF00595213
Isser Brody, The ultrastructure of the epidermis in lichen ruber planus as revealed by electron microscopy Journal of Ultrastructure Research. ,vol. 28, pp. 161- 177 ,(1969) , 10.1016/S0022-5320(69)90077-X
Isser Brody, The ultrastructure of the epidermis in lichen ruber planus as revealed by electron microscopy Journal of Ultrastructure Research. ,vol. 28, pp. 178- 190 ,(1969) , 10.1016/S0022-5320(69)90078-1
Martin M. Black, The pathogenesis of lichen planus. British Journal of Dermatology. ,vol. 86, pp. 302- 305 ,(1972) , 10.1111/J.1365-2133.1972.TB02233.X
N.G. El-labban, Ivor R.H. Kramer, Nuclear bodies in oral lichen planus Journal of Ultrastructure Research. ,vol. 40, pp. 470- 479 ,(1972) , 10.1016/S0022-5320(72)80036-4
Hermann Pinkus, Lichenoid Tissue Reactions Archives of Dermatology. ,vol. 107, pp. 840- 846 ,(1973) , 10.1001/ARCHDERM.1973.01620210008002
A. Jarrett, K. Mary Witham, Joan A. Hardy, Enzyme changes in lichen planus Archives of Dermatological Research. ,vol. 252, pp. 257- 266 ,(1975) , 10.1007/BF00560365