Daily ingestion of alginate reduces energy intake in free-living subjects

摘要: Sodium alginate is a seaweed-derived fibre that has previously been shown to moderate appetite in models of acute feeding. The mechanisms underlying this effect may include slowed gastric clearance and attenuated uptake from the small intestine. In order assess whether could be effective as means control free-living adults, 68 males females (BMI range: 18.50-32.81 kg/m(2)) completed randomised, controlled two-way crossover intervention compare effects 7 day daily ingestion strong-gelling sodium formulation against control. A with high-guluronate content was chosen because, upon ingestion, it forms strong gel presence calcium ions. Daily preprandial produced significant 134.8 kcal (7%) reduction mean energy intake. This reduced intake underwritten by reductions carbohydrate, sugar, fat, saturated fat protein intakes. absence any interaction between main preload type those gender, BMI classification and/or timing delivery indicates efficacy treatment for individuals different settings. These findings suggest possible role future management overweight obesity.