The cell biology of fat expansion.

摘要: Adipose tissue is a complex, multicellular organ that profoundly influences the function of nearly all other systems through its diverse metabolite and adipokine secretome. Adipocytes are primary cell type adipose play key role in maintaining energy homeostasis. The efficiency with which responds to whole-body energetic demands reflects ability adipocytes adapt an altered nutrient environment, has profound systemic implications. Deciphering adipocyte biology important component understanding how aberrant physiology expanding contributes metabolic dysregulation associated obesity.