Tumor Immunogenicity Induced by the Local Occurrence of Il-2

摘要: In natural situations, few immunogenic tumors escape destruction by immune reaction on the part of host. Nevertheless, spontaneous may often be antigenic owing to abnormal proteins or peptides expressed their cell membrane. They are not immunogenic, however, because cells produce several suppressor factors that hamper local and systemic reactions. Attraction paralysis a tumor large variety leukocytes through release cytokines chemotactic factors1 means found heavily infiltrated kind. It is uncertain, whether reactive infiltrate impedes growth prognostic significance2.