Regulat-INGs in tumors and diseases: Focus on ncRNAs.
作者： Marjorie Gournay , Mathieu Paineau , Jérôme Archambeau , Rémy Pedeux
DOI: 10.1016/J.CANLET.2019.01.006
关键词:
摘要: Abstract ING family genes (Inhibitor of Growth) are tumor suppressor that play a vital role in cell homeostasis. It has been shown their expression is lost or diminished many cancers and other diseases. The main mechanisms by which they regulated oncogenesis have not yet fully elucidated. involvement non-coding RNAs (ncRNAs) particular microRNAs (miRNAs) post-transcriptional gene regulation well established. miRNAs short sequences (18–25 nucleotides) can bind to the 3 ′UTR sequence targeted messenger RNA (mRNA), leading its degradation translational repression. Interactions between described some but also opens up new fields investigation, particularly for therapies. In this review, we will summarize regulatory at protein level focus on interactions with ncRNAs.
sci-hub.se 参考文章(155)
Kimberly Stegmaier, Shona Pendse, George F Barker, Patricia Bray-Ward, David C Ward, Kate T Montgomery, Kenneth S Krauter, Carol Reynolds, Jeffrey Sklar, Mia Donnelly, None, Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood. Blood. ,vol. 86, pp. 38- 44 ,(1995) , 10.1182/BLOOD.V86.1.38.BLOODJOURNAL86138
David P Bartel, MicroRNAs: Genomics, Biogenesis, Mechanism, and Function Cell. ,vol. 116, pp. 281- 297 ,(2004) , 10.1016/S0092-8674(04)00045-5
An Yan, Chunyu Yang, Zhibo Chen, Chunhong Li, Li Cai, MiR-761 Promotes Progression and Metastasis of Non-Small Cell Lung Cancer by Targeting ING4 and TIMP2. Cellular Physiology and Biochemistry. ,vol. 37, pp. 55- 66 ,(2015) , 10.1159/000430333
Ettore Appella, Mariko Kitahama-Shiseki, Remy M. Pedeux, Masayuki Shiseki, Curtis C. Harris, Makoto Nagashima, Jun Yokota, Koh Miura, Yuichiro Higashimoto, Hitoshi Onogi, Shu Okamura, p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. Cancer Research. ,vol. 63, pp. 2373- 2378 ,(2003)
Nastaran Mohammadi Ghahhari, Sadegh Babashah, None, Interplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelial-mesenchymal transition in cancer. European Journal of Cancer. ,vol. 51, pp. 1638- 1649 ,(2015) , 10.1016/J.EJCA.2015.04.021
Igor Garkavtsev, Irina A. Grigorian, Valeria S. Ossovskaya, Mikhail V. Chernov, Peter M. Chumakov, Andrei V. Gudkov, The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control Nature. ,vol. 391, pp. 295- 298 ,(1998) , 10.1038/34675
Feng Zhang, Xutao Zhang, Jin Meng, Yong Zhao, Xinli Liu, Yanxia Liu, Yukun Wang, Yuhua Li, Yang Sun, Zhipeng Wang, Qibing Mei, Tao Zhang, ING5 inhibits cancer aggressiveness via preventing EMT and is a potential prognostic biomarker for lung cancer Oncotarget. ,vol. 6, pp. 16239- 16252 ,(2015) , 10.18632/ONCOTARGET.3842
Dong-liang Chen, Dong-sheng Zhang, Yun-xin Lu, Le-zong Chen, Zhao-lei Zeng, Ming-ming He, Feng-hua Wang, Yu-hong Li, Hui-zhong Zhang, Helene Pelicano, Wei Zhang, Rui-hua Xu, microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer Oncotarget. ,vol. 6, pp. 10868- 10879 ,(2015) , 10.18632/ONCOTARGET.3451
Wen-feng Gou, Dao-fu Shen, Xue-feng Yang, Shuang Zhao, Yun-peng Liu, Hong-zhi Sun, Rong-jian Su, Jun-sheng Luo, Hua-chuan Zheng, ING5 suppresses proliferation, apoptosis, migration and invasion, and induces autophagy and differentiation of gastric cancer cells: a good marker for carcinogenesis and subsequent progression. Oncotarget. ,vol. 6, pp. 19552- 19579 ,(2015) , 10.18632/ONCOTARGET.3735
Y. Shimada, A. Saito, M. Suzuki, E. Takahashi, M. Horie, Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor Cytogenetic and Genome Research. ,vol. 83, pp. 232- 235 ,(1998) , 10.1159/000015188