Stabilized HIV-1 peptide constructs comprising the gp120 C5 domain and gp41 hydrophilic domain
作者： Birger Sørensen , Einar Tønnes Lange , Per Bengtsson , Jens Olof Holmberg , Maja Sommerfelt Grønvold
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摘要: Disclosed is a method for treatment of HIV related diseases comprising targeting complexes between on the one hand C5 domain gp120 and other gp41 or C2 gp120. The may be stabilised by administering compounds, such as antibodies, capable directly interacting with stabilising complex, immunizing gp41/C2 derived material so to induce antibodies that bind stabilise complex.
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