Anticandidal activity of Cassia fistula and its effect on ergosterol biosynthesis.
作者： Md Irshad , Sheikh Shreaz , Nikhat Manzoor , Luqman A. Khan , M. Moshahid A. Rizvi
DOI: 10.3109/13880209.2010.544318
关键词:
摘要: Context: Cassia fistula Linn. (Caesalpiniaceae) has been used in folk medicine. Anthraquinone derivative rhein having antimicrobial properties is actively present C. fruit. Although, as yet there no study of its anticandidal potential.Objective: The was conducted to determine the phytochemical composition fruit pulp and seed extract their effect on Candida albicans ATCC 10261, glabrata 90030 tropicalis 750, respectively.Materials methods: The extracts were tested for phytochemicals by various standard methods identified thin-layer chromatography. The activity determined minimum inhibitory concentration (MIC), growth curve studies, cytotoxicity ergosterol estimation assay.Results: The showed high content phenolic compounds. Rhein both extracts, Rf 0.38. MICs obtained with albicans, gl...
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