Long term follow-up and risk of breast cancer after a radial scar or complex sclerosing lesion has been identified in a benign open breast biopsy

摘要: Abstract Aims Radial scars (RS)/complex sclerosing lesions (CSL) are rare, benign breast of unknown aetiology. Associations with cancer have been suggested particularly larger lesions. This study aims to identify the risk developing subsequent after excision a RS/CSL respect lesion size and compared expected rates in normal UK population. Methods A prospective cohort analysis was performed on patients diagnosed benign, open biopsy specimens over 20-year period. The rate development Subjects were divided into two groups according compared. Results 149 women without proliferative disease followed for an average 68 months. Five developed cancer, equating 0.84% per year. compares 0.32% year population (RR 2.6, 95% CI 0.86–6.0). There cancers RS group three CSL group, P  = 0.64. Conclusions finds no evidence suggest that greater than 10 mm any those below (RS). Women treated do not need additional follow-up beyond routine mammographic screening. Additional surveillance should only be if there is associated pathology indicating increased malignancy.