Age-related changes to the neural correlates of working memory which emerge after midlife
作者： Helen N. Macpherson , David J. White , Kathryn A. Ellis , Con Stough , David Camfield
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摘要: Previous research has indicated that the neural processes which underlie working memory change with age. Both age-related increases and decreases to cortical activity have been reported. This study investigated stages of are most vulnerable changes after midlife. To do this we examined age-differences in 13Hz steady state visually evoked potential (SSVEP) associated a spatial delayed response task. Participants were 130 healthy adults separated into midlife (40 60 years) an older group (61 82 years). Relative group, demonstrated greater bilateral frontal during encoding pattern was related better performance. In contrast, evidence under activation identified over left regions retrieval. Findings from suggest midlife, under-activation retrieval contributes decline
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