Is Complexity of Work Associated with Risk of Dementia?: The Canadian Study of Health and Aging

摘要: The authors evaluated the association of complexity work with data, people, and things incidence dementia, Alzheimer's disease, vascular dementia in Canadian Study Health Aging, while adjusting for work-related physical activity. Aging is a 10-year population study, from 1991 to 2001, representative sample persons aged 65 years or older. Lifetime job history allowed application scores classification Analyses included 3,557 subjects, whom 400 were incident cases, including 299 disease 93 dementia. In fully adjusted Cox regression models, high people reduced risk (hazard ratios 0.66 (95% confidence interval: 0.44, 0.98) 0.72 0.52, 0.99), respectively) but not disease. For hazard 0.36 0.15, 0.90) 0.50 0.25, 1.00) things. Subgroup analyses according median duration (23 years) principal occupation showed that associations varied employment. High appears be associated effects may vary subtype.