Role of phytochemicals in prevention and treatment of prostate cancer.

摘要: This review paper focuses on the role of phytochemicals in prevention and treatment prostate cancer. Interest phytoestrogens goes back over 30 years which initial research was directed at estrogenic effects this class compounds; particularly breeding farm animals. In order to determine cancer risk it is necessary demonstrate that their addition mens diet leads reduction or progression through direct evaluation. With use cell culture approaches with human lines soy isoflavone genistein has shown inhibition serum growth factor-stimulated proliferation cells suggesting phytochemical have potential for slowing cells. Among animal models such are demonstrated by biomarkers cellular mechanisms action involved prostate-specific antigen induction p21 a py p53-independent pathway epidermal factor autophosphorylation NF-kappa B activation. Since depend matrix they delivered careful examination food materials suitable pre-clinical important prior health claims its usefulness prostrate