Algerian Sonchus oleraceus L.: a comparison of different extraction solvent on phytochemical composition, antioxidant properties and anti-cholinesterase activity
作者： Lay Kek Teh , Muhd Hanis Md Idris , Hayette Ayed , Nedjoud Grara , Aissam Bousbia
DOI: 10.1007/S13596-021-00553-Y
关键词:
摘要: Aerial parts of Sonchus oleraceus L. were studied for the antioxidant and anti-cholinesterase activities in different solvent fractions. Extracts/fractions analysed total phenolic, flavonoid flavonol contents. The chemical constituents most active extracts/fractions using LC–MS/QTOF positive ion mode. Ethyl acetate butanolic fractions exhibited highest activity DPPH, galvinoxyl phenanthroline assays due to high contents phenolics, flavonoids flavonols. Whereby alkaloid extract had scavenging ABTS•+ assay. Besides, methanolic was noted inhibitory effect against acetylcholinesterase. Total 24 compounds identified by which phenolic acids, sesquiterpene lactones phenylpropanoid derivatives. As conclusion, study revealed that aerial S. are potential sources natural compounds.
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Honglian Shi, Noriko Noguchi, Etsuo Niki, Galvinoxyl method for standardizing electron and proton donation activity Methods in Enzymology. ,vol. 335, pp. 157- 166 ,(2001) , 10.1016/S0076-6879(01)35240-0
Jeffrey L Cummings, Gustavo Alva, Relative tolerability of Alzheimer's disease treatments. Psychiatry (Edgmont (Pa. : Township)). ,vol. 5, pp. 27- 36 ,(2008)
H. Gutzmann, D. Hadler, Sustained efficacy and safety of idebenone in the treatment of Alzheimer's disease: update on a 2-year double-blind multicentre study. Journal of Neural Transmission-supplement. ,vol. 54, pp. 301- 310 ,(1998) , 10.1007/978-3-7091-7508-8_30
Schmitt-Schillig S, Eckert Gp, Müller We, Schaffer S, Antioxidant properties of Mediterranean food plant extracts: geographical differences. Journal of Physiology and Pharmacology. ,vol. 56, pp. 115- 124 ,(2005)
Vijay Kumar Daroji, B S Jayashree, Yogendra Nayak, M K Unnikrishnan, Geetha Mathew, H Venkatachalam, Antidiabetic activity of 3-hydroxyflavone analogues in high fructose fed insulin resistant rats. Excli Journal. ,vol. 13, pp. 1055- 1074 ,(2014) , 10.17877/DE290R-6937
Akihiko Nunomura, George Perry, Gjumrakch Aliev, Keisuke Hirai, Atsushi Takeda, Elizabeth K. Balraj, Paul K. Jones, Hossein Ghanbari, Takafumi Wataya, Shun Shimohama, Shigeru Chiba, Craig S. Atwood, Robert B. Petersen, Mark A. Smith, Oxidative damage is the earliest event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. ,vol. 60, pp. 759- 767 ,(2001) , 10.1093/JNEN/60.8.759
Lakshmipathy Inbathamizh, E. Padmini, QUINIC ACID AS A POTENT DRUG CANDIDATE FOR PROSTATE CANCER – A COMPARATIVE PHARMACOKINETIC APPROACH Asian Journal of Pharmaceutical and Clinical Research. ,vol. 6, pp. 106- 112 ,(2013)
Neda Nićiforović, Helena Abramovič, Sinapic Acid and Its Derivatives: Natural Sources and Bioactivity. Comprehensive Reviews in Food Science and Food Safety. ,vol. 13, pp. 34- 51 ,(2014) , 10.1111/1541-4337.12041
Tushar Dhanani, Sonal Shah, NA Gajbhiye, Satyanshu Kumar, None, Effect of extraction methods on yield, phytochemical constituents and antioxidant activity of Withania somnifera Arabian Journal of Chemistry. ,vol. 10, pp. S1193- S1199 ,(2017) , 10.1016/J.ARABJC.2013.02.015
M. A. Lovell, W. R. Markesbery, Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease Nucleic Acids Research. ,vol. 35, pp. 7497- 7504 ,(2007) , 10.1093/NAR/GKM821