Biotransformation of (+)-(1R)- and (−)-(1S)-fenchone by the larvae of common cutworm (Spodoptera litura)

摘要: Abstract Biotransformation of (+)-(1 R )- and (−)-(1 S )-fenchone in Spodoptera litura larvae has been investigated. (+)- (−)-Fenchone were regio- stereo-selective hydroxylated. (+)-Fenchone was transformed to one new terpenoid, ,4 )-3-oxo-2,2,4-trimethyl-cyclopentylacetic acid four known terpenoids, ,6 )-6- exo -hydroxyfenchone, endo )-10-hydroxyfenchone ,5 )-5- -hydroxyfenchone. -hydroxyfenchone acid. C-6 position (−)-fenchone progressing the carboxylic acid, which is characteristically metabolic pathway compared with any other biocatalysts. Intestinal bacteria from frass did not participate metabolism (−)-fenchone.