Mimotope vaccines: epitope mimics induce anti-cancer antibodies.

摘要: Mimotopes are epitope-mimicking structures. When applied for immunizations they induce desired antibody specificities exclusively based on the principle of molecular mimicry. This is important as antibodies directed against tumor-associated antigens may harbor diverse biological effects depending their epitope specificity. Thus inhibit or promote tumor growth. review gives an update different vaccination strategies mimotope concept.