Monoclonal antibody 175 targeting the egf receptor and derivatives and uses thereof
作者： Terrance Grant Johns , Antony Wilks Burgess , Llyod J. Old , Andrew Mark Scott
DOI:
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摘要: The present invention relates to antibodies, particularly antibody 175, and fragments thereof or antibodies derived therefrom, which bind the EGF receptor, amplified overexpressed epidermal growth factor receptor (EGFR) de2-7 EGFR truncation of EGFR. These are useful in diagnosis treatment cancer. Recombinant hybrid having variable region heavy light chain sequence(s) 175 also provided. may be used therapy combination with chemotherapeutics anti-cancer agents and/or other thereof.
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