Prevalence of admission hyperglycaemia across clinical subtypes of acute stroke.

摘要: Admission hyperglycaemia is known to be an independent risk factor for poor outcome following stroke but the prevalence of across clinical subtypes acute unknown. Any novel therapy designed modulate plasma glucose in phase should applicable most patients all subtypes. It has been suggested that admission only present more severe strokes, indicating a predetermined prognosis, and therefore intervention would unlikely alter subsequent outcome. Over 9-month period consecutive were assessed upon hospital evaluate subtype (total anterior circulation syndrome [TACS], partial [PACS], lacunar [LACS], or posterior [POCS]) concentration. values classified as above 6·0 mmol/L 6·9 mmol/L. 303 assessed. There no statistically significant differences between terms age, sex, diabetes mellitus. Patients with TACS likely have primary intracerebral haemorrhage (p<0·001, chi-squared test), greater than (p=0·002, higher mean (p=0·003, Mann Whitney U-test) those non-TACS 50% within each had on (figure). common patients, exists range subtypes, although significantly it not restricted these patients. If treatment found effective, over two-thirds These findings provide The man complained impotence was receiving trazodone prescribed by urologist. His other medications quinapril, meclizine, omeprazole. He did smoke drink alcohol. On examination, his blood pressure 140/90 mm Hg. respiratory, cardiovascular, abdominal assessments normal. bilaterally absent ankle jerks bilateral decreased vibratory sensation feet up ankles. initial series laboratory investigations showed marginally low haemoglobin corpuscular volume. Blood urea nitrogen, serum creatinine, electrolytes, liver function tests normal, well urinalysis thyroid profile. Because persistent impotence, urologist sildenafil. patient reported improvement sexual performance. At this time, we screened him rule out sex-hormone abnormalities. total testosterone 150 ng/dL (normal 260–990 ng/dL), free 0·80 1·60–3·30 prolactin concentration 80·4 ng/mL <15 ng/mL). Serum follicle-stimulating hormone luteinising concentrations normal limits. A magnetic resonance scan pituitary fossa 4 microadenoma. treated bromocriptine. We came another case missed hyperprolactinaemia before sildenafil became available. aged 57 years diagnosed mellitus 2 months previously. complications retinopathy, nephropathy, coronary artery disease, peripheral vascular he impotence. History started injections testosterone. Presently, using patches. Physical examination unremarkable pinprick big toes. included nifedipine, indapamide, probucol, fluoxetine. advised appropriate done 500 mg metformin twice daily because high sugar concentrations. results 149·1 limit ng/mL), testosterone, hormone, However, evidence tumour abnormality. bromocriptine 2·5 at night. normalised there dramatic potency after starting concentrations, however, remained required continued cases show importance systematic assessment cause prescription sildenafil, Chan-Tack. Many who also disorders are fully investigated, since attributed autonomic neuropathy. Diabetic neuropathy lead failure erection only, libido remaining intact. Loss suspicion hormonal History, physical testicular volume consistency, shape penis, penile pulsations, detailed neurological brain, spinal cord, nerve lesions first steps. gonadotropin, measured renal, hepatic, disorders.