Anti-tick Vaccine Development: Status and Perspectives

摘要: Ticks (Acarina: Arachnida: Arthropoda) are obligate, nonpermanent ectoparasites of terrestrial vertebrates. In arthropods, ticks second only to mosquitoes in the number pathogens they transmit people, domestic pets, livestock, and wild animals. vectors a variety human diseases, including Rocky Mountain spotted fever, Lyme disease, Colorado tick tickborne encephalitis, babesiosis, tularemia, tick-borne relapsing fever. addition, other maladies due bites, such as paralysis, toxicosis, anaphylaxis, common. Each year, worldwide public health agricultural industry costs tick-transmitted diseases estimated be range several billion U.S. dollars. To date, control has relied heavily on chemical pesticides (acaricides). The excessive use resulted environmental contamination, food safety concerns, pesticide resistance. Consequently, molecular technology develope anti-tick vaccines is an essential alternative strategy disease control. Recent studies status vaccine development reviewed this chapter.