Sulphur promoted C(sp3)–C(sp2) cross dehydrogenative cyclisation of acetophenone hydrazones with aldehydes: efficient synthesis of 3,4,5-trisubstituted 1H-pyrazoles
作者： Rajeshwer Vanjari , Tirumaleswararao Guntreddi , Saurabh Kumar , Krishna Nand Singh
DOI: 10.1039/C4CC08210A
关键词:
摘要: A novel strategy for the cross dehydrogenative coupling (CDC) of acetophenone hydrazones and aldehydes has been developed synthesis highly substituted pyrazoles. This work, first time, uses elemental sulfur as a promoter well hydrogen acceptor in effecting Csp3–Csp2 bond formation via C–H activation.
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