Dipeptide compounds having pharmaceutical activity and compositions containing them

作者: Angelo Carenzi , Davide Della Bella , Alberto Pilotto , Mario Portelli

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摘要: The compounds of formula (I) wherein the group (II) represents residue a natural amino acid selected from consisting glycine, alanine, beta-alanine, phenylalanine, isoleucine, methionine, proline, aspartic and arginine; R hydrogen atom or C1-C4 alkyl; their acid-addition salts with pharmaceutically acceptable organic inorganic acids; are useful in preventive curative treatment pathologic syndromes due to lowering glutathione (GSH) levels.

参考文章(4)
Arthur A. Patchett, Edward W. Tristram, Elbert E. Harris, Matthew J. Wyvratt, Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them ,(1979)
Eike Dr Rer Nat Meinetsberger, Rainer Josef Dr Rer Na Klauser, Klaus-Peter Dr Rer Bichlmayer, Substituted carboxylic acid derivatives, process for their preparation, and pharmaceuticals ,(1983)