Transforming growth factor beta (TGF-β) and inflammation in cancer

作者: Brian Bierie , Harold L. Moses

DOI: 10.1016/J.CYTOGFR.2009.11.008

关键词:

摘要: … populations in this context likely enhances the classic role for TGF-β in immune suppression … expression of an activated TGF-β ligand or expression of a constitutively active TβRI could …

参考文章(132)
Pinku Mukherjee, Amelia R. Ginardi, Cathy S. Madsen, Teresa L. Tinder, Fred Jacobs, Joanne Parker, Babita Agrawal, B. Michael Longenecker, Sandra J. Gendler, MUC1-specific CTLs are non-functional within a pancreatic tumor microenvironment. Glycoconjugate Journal. ,vol. 18, pp. 931- 942 ,(2001) , 10.1023/A:1022260711583
Mary Helen Barcellos-Hoff, Evangeline Easterly, Jonathan M. Yingling, Carlos L. Arteaga, Incheol Shin, Jae Youn Yi, Roy Zent, Rebecca S. Muraoka-Cook, Activated type I TGFbeta receptor (Alk5) kinase confers enhanced survival to mammary epithelial cells and accelerates mammary tumor progression Lawrence Berkeley National Laboratory. ,(2005)
Cheng-Long Huangi, Hiroyasu Yokomise, Kazumasa Ogasawara, Kiichi Kajino, Keiichi Kontani, Akira Yamauchi, Osamu Taguchi, Shozo Fujino, Spontaneous elicitation of potent antitumor immunity and eradication of established tumors by administration of DNA encoding soluble transforming growth factor-b II receptor without active ,(2006)
Kenneth B. Ewan, Gopalan Shyamala, Shraddha A. Ravani, Yang Tang, Rosemary Akhurst, Lalage Wakefield, Mary Helen Barcellos-Hoff, Latent Transforming Growth Factor-β Activation in Mammary Gland The American Journal of Pathology. ,vol. 160, pp. 2081- 2093 ,(2002) , 10.1016/S0002-9440(10)61158-3
M P Bell, S N Ho, J A Augustine, J J Ruegemer, R T Abraham, D J McKean, J W Schlager, Regulatory effects of transforming growth factor-beta on IL-2- and IL-4-dependent T cell-cycle progression. Journal of Immunology. ,vol. 144, pp. 1767- 1776 ,(1990)
Adriano Fontana, Stefan Bodmer, Karl Frei, Ursula Malipiero, Christine Siepl, Expression of TGF-beta 2 in human glioblastoma: a role in resistance to immune rejection? Ciba Foundation symposium. ,vol. 157, pp. 232- 241 ,(1991) , 10.1002/9780470514061.CH15
A S Fauci, H C Lane, L M Wakefield, A B Roberts, M B Sporn, J H Kehrl, A H Rook, D B Burlington, Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness. Journal of Immunology. ,vol. 136, pp. 3916- 3920 ,(1986)
Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn, Takuya Nakayama, Jan L. Christian, Rainer Heuchel, Susumu Itoh, Masahiro Kawabata, Nils-Erik Heldin, Carl-Henrik Heldin, Peter ten Dijke, Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling Nature. ,vol. 389, pp. 631- 635 ,(1997) , 10.1038/39369
June-Chul Lee, Kyung-Mi Lee, Dong-Wan Kim, Dae Seog Heo, Elevated TGF-β1 Secretion and Down-Modulation of NKG2D Underlies Impaired NK Cytotoxicity in Cancer Patients The Journal of Immunology. ,vol. 172, pp. 7335- 7340 ,(2004) , 10.4049/JIMMUNOL.172.12.7335
Bond Almand, Joseph I. Clark, Ekaterina Nikitina, James van Beynen, Nicholas R. English, Stella C. Knight, David P. Carbone, Dmitry I. Gabrilovich, Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. Journal of Immunology. ,vol. 166, pp. 678- 689 ,(2001) , 10.4049/JIMMUNOL.166.1.678