作者: Gary M. Brittenham , Harvey G. Klein , James P. Kushner , Richard S. Ajioka
DOI: 10.1182/ASHEDUCATION-2001.1.422
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摘要: This paper examines the current state of blood supply in US and focuses on potential for augmenting availability by attention to iron status donors. Increasing demands are being made upon national as rates donation declining, part because loss donors a result enhanced screening testing procedures. Iron-related means expanding include use from individuals undergoing therapeutic phlebotomy hereditary hemochromatosis enhancing retention commitment women childbearing age using supplementation prevent deficiency. In Section I, Dr. Klein discuss circumstances responsible decline population eligible donors, including public attitudes toward donation, factors influencing centers, effects increased maintain safety supply. II, Drs. Kushner Ajioka focus consequences decision Food Drug Administration (FDA) develop recommendations permit centers collect patients with distribute this obtained without disease labeling if all other procedures passed. After summarizing pathophysiology hemochromatosis, heterozygotes homozygotes is considered. III, Brittenham reviews low dose, short-term carbonyl age. Replacing lost at can help deficiency and, decreasing deferral, enhance who give regularly. He emphasizes iron-related recruitment