Sequencing of Difficult DNA Regions by SAM Sequencing
作者： Keith R. Mitchelson
DOI: 10.1007/978-1-60761-944-4_6
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摘要: Nucleotide analogues are used increasingly in medicine and biotechnology to effect DNA sequence change, principally via clastogenic transcriptional effects. This article, however, discusses the use of mutagenic nucleotide improve sequencing recalcitrant repetitive motifs. Guidance technical practical approaches that support this approach with different technologies is provided, including for high-throughput technologies.
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