DNA Chips Give New View of Classic Test

作者: E. Pennisi

DOI: 10.1126/SCIENCE.283.5398.17

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摘要: By now you would think that cell biologists knew everything there is to know about how fibroblast cells in culture respond serum after being deprived of it. But work described on page 83 shows be wrong. The standard view has been serum9s growth factors and other nutrients switch the fibroblasts9 proliferation program. by using a DNA chip allowed them monitor more than 8600 genes at once, researchers have found not only stimulates division, but also turns needed wound healing. Indeed, behave much as if they were still intact tissue, opening way, say, chips study such complex issues cell-to-cell interactions.

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