摘要: When circulating blood comes in contact with an artificial surface, certain plasma proteins are deposited virtually instantaneously. Blood platelets, accordingly, do not make direct materials the bloodstream, but interact surface layer of protein (Table 1). The nature surface-bound varies and way which it is introduced circulation. However, most synthetic become coated predominantly fibrinogen [1] gradually changes time so that eventually does react anti-fibrinogen antibodies. Blood-surface interaction rapidly generates thrombin, through activation coagulation mechanism, exposure platelets to thrombin likely be a major pathway platelet activation. Finally, surfaces may generate shear stresses, leading mechanical platelets.
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