作者: Dale F. Mierke , Maria Pellegrini
DOI: 10.1016/B0-12-475570-4/01127-6
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摘要: Receptor–ligand interaction is the fundamental step in initiation of a signal from outside to inside cell, process often called transduction. The fidelity this signaling, and therefore between receptor specific ligand, integral cellular vitality function. Defining elements required for receptor–ligand interactions provides novel insight into development therapeutic agents control (enhance or inhibit) signaling event treat various disease states.