Cure of recurrent medulloblastoma: the contribution of surgical resection at relapse.

摘要: BACKGROUND Recurrent medulloblastoma has long been considered universally fatal. In spite of attempts to improve its treatment, only rarely have term survivors documented in the world's medical literature. Although treatment primary is well established and includes surgical excision, postsurgical irradiation, and, more recently, chemotherapy, there no for recurrence. Current guidelines dictate experimental use some encouraging results; yet increase survival documented. METHODS This article presents a case cured recurrent which intervention at time recurrence was excision. addition, review literature presented, evaluates chemotherapeutic trials involving cases medulloblastoma. RESULTS The authors were surprised find that longest multiple had undergone reoperation The authors' case, as described literature, point valid alternative largely ignored management medulloblastoma. CONCLUSIONS Reoperation brain tumors received surprisingly little attention Yet, this demonstrate, useful intervention. Cancer 1997; 79:1241-7. © 1997 American Society.