The multi-module, multi-resolution system (M3R): a novel small-animal SPECT system.

作者: Jacob Y. Hesterman , Matthew A. Kupinski , Lars R. Furenlid , Donald W. Wilson , Harrison H. Barrett

DOI: 10.1118/1.2432071

关键词:

摘要: We have designed and built an inexpensive, high-resolution, tomographic imaging system, dubbed the multi-module, multi-resolution or M3R. Slots machined into system shielding allow for interchange of pinhole plates, enabling to operate over a wide range magnifications with virtually any desired configuration. The flexibility allows optimization specific tasks also modifications necessary due improved detectors, electronics, knowledge construction (e.g., sensitivity optimization). provide overview M3R, focusing primarily on design construction, aperture calibration methods. Reconstruction algorithms will be described reconstructed images presented.

参考文章(17)
FRANK WILKINSON, CHAPTER 13 – Scintillators Emission Tomography#R##N#The Fundamentals of PET and SPECT. pp. 229- 254 ,(2004) , 10.1016/B978-012744482-6.50016-8
Yi-Chun Chen, Lars R. Furenlid, Donald W. Wilson, Harrison H. Barrett, Calibration of Scintillation Cameras and Pinhole SPECT Imaging Systems Springer, Boston, MA. pp. 195- 201 ,(2005) , 10.1007/0-387-25294-0_12
R.E. Zimmerman, S.C. Moore, A. Mahmood, Performance of a triple-detector, multiple-pinhole SPECT system with iodine and indium isotopes IEEE Symposium Conference Record Nuclear Science 2004.. ,vol. 4, pp. 2427- 2429 ,(2004) , 10.1109/NSSMIC.2004.1462746
Steven R Meikle, Peter Kench, Michael Kassiou, Richard B Banati, Small animal SPECT and its place in the matrix of molecular imaging technologies. Physics in Medicine and Biology. ,vol. 50, ,(2005) , 10.1088/0031-9155/50/22/R01
Liying Chen, Harrison H. Barrett, Optimizing lens-coupled digital radiographic imaging systems based on model observers' performance Medical Imaging 2003: Image Perception, Observer Performance, and Technology Assessment. ,vol. 5034, pp. 63- 70 ,(2003) , 10.1117/12.480331
Kevin Gross, Matthew A. Kupinski, Todd E. Peterson, Eric Clarkson, Optimizing a Multiple-Pinhole SPECT System Using the Ideal Observer Medical Imaging 2003: Image Perception, Observer Performance, and Technology Assessment. ,vol. 5034, pp. 314- 322 ,(2003) , 10.1117/12.480336
Jacob Y. Hesterman, Matthew A. Kupinski, Lars R. Furenlid, Donald W. Wilson, Experimental task-based optimization of a four-camera variable-pinhole small-animal SPECT system Medical Imaging 2005: Image Perception, Observer Performance, and Technology Assessment. ,vol. 5749, pp. 300- 309 ,(2005) , 10.1117/12.594386
Tobias Funk, Philippe Després, William C. Barber, Kanai S. Shah, Bruce H. Hasegawa, A multipinhole small animal SPECT system with submillimeter spatial resolution. Medical Physics. ,vol. 33, pp. 1259- 1268 ,(2006) , 10.1118/1.2190332
Matthew A. Kupinski, John W. Hoppin, Eric Clarkson, Harrison H. Barrett, Ideal-observer computation in medical imaging with use of Markov-chain Monte Carlo techniques. Journal of The Optical Society of America A-optics Image Science and Vision. ,vol. 20, pp. 430- 438 ,(2003) , 10.1364/JOSAA.20.000430