Effects of conventional ultrafiltration on renal performance during adult cardiopulmonary bypass procedures.

作者: David W Holt , Lee Stichka , Scott Turner , Rick A Kuntz , Bryan Thacker

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摘要: Ultrafiltration has been used successfully in a variety of applications the perioperative setting to assist hemoconcentration and volume reduction. This study was designed investigate effects aggressive conventional hemofiltration on bypass urine production, fluid balance, renal performance 24 hours after procedures adult population. A prospective, randomized determine ultrafiltration (CUF) during while monitoring dynamics intraoperatively 24-hour post-bypass period. Study group 1 (CUF, n = 49) compared control 2 (non-CUF, 47) by values, additions, packed red cell (PRC) use throughout procedure. The mean total CUF removed from 5781 +/- 2612. There were no differences pre-bypass, bypass, or operating room (OR) between two groups. totals significantly higher (2389 895) than (2035 895). ending hematocrit also lower (26 2.0) (30 6.0). OR PRC additions (395 699) (204 300). non-CUF experienced greater balance (3006 868) with (744 1271). No significant pre- postoperative creatinine values observed. Aggressive can be safely cardiopulmonary population reduce accumulation elevate without effecting intraoperative production.

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