Guillain — Barré Syndrome in Inflammatory Joint Diseases

摘要: Background. Guillain — Barre syndrome (GBS) in joints inflammatory diseases is described several surveys, and many clinical pathogenic aspects of this peripheral neuropathy (PNP) remain obscure. Objective. To evaluate the incidence nature course GBS rheumatoid arthritis (RA), chlamydia urogenital reactive (ReA), psoriatic (PA) ankylosing spondylitis (AS), to study issues structure neuropathy, identify risk factors. Material methods. The included 416 patients with joint diseases, among them 131 RA patients, 101 ReA, 76 PA 108 AS. average age examined persons was 45, 32, 42 38 years old, respectively, disease duration 10, 4, 12 11 years, male female ratio — 1 : 5, 1 : 1, 1 : 2 10 : 1. Results. develops 3, 5 9 % RA, PA, ReA AS, or 24, 17, 26 27 % these PNP that closely related presence tendovaginitis at all severity articular syndrome, depends on digital arteritis, hypothyroidism, Sjogren’s ReA — on violations excitability myocardium heart electrical conduction, A — on exudative form cutaneous psoriasis, AS — on osteoporosis, immune disorders, processes endothelial dysfunction vascular changes physic-chemical adsorption-rheological viscoelastic relaxation properties blood participate pathogenesis GBS. Conclusion. correlated laboratory signs future such active detection pathology nervous system will be useful for timely follow-up rehabilitation, and, seropositive results by anti-cyclic citrullinated peptide antibodies are factor PNP.