Involvement of TSP1 and MMP9/NGAL in angiogenesis during orthodontic periodontal remodeling.
作者： Petra Surlin , Isabela Silosi , Anne Marie Rauten , Manole Cojocaru , Lili Foia
DOI: 10.1155/2014/421029
关键词:
摘要: In the present study aim was to measure levels of Thrombospondin-1 (TSP1) and Lipocalin-2/matrix metalloproteinase 9 (MMP9/NGAL) complex in gingival crevicular fluid (GCF) at different time points orthodontic treatment, determine relationship between these values those total-matrix (MMP9) theirs implication angiogenesis balance, situation a good control bacterial plaque, emphasizing role TSP1 MMP9/NGAL complex. GCF samples were collected from 16 young patients requiring upper canine distalization (test tooth) with first premolar extraction. The contralateral (control free force. For appliance, brackets Roth 0.018 inch 0.012 inch NiTi archwire laceback used. TSP1, MMP9/NGAL, MMP9 increased 1 hour before activation appliance maximum 8 hours for 72 TSP1. results show change this method treatment. powerful correlation suggests their stronger involvement processes PDL during periodontal remodeling, healthy periodontium plaque.
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