Uptake of iron from hemoglobin and the haptoglobin-hemoglobin complex by hemolytic bacteria.

摘要: The abilities of Staphylococcus aureus and Streptococcus pyogenes to remove iron from mouse 59Fe hemoglobin that was either in free form or complexed with human haptoglobin, were evaluated. the amphibian Taricha granulosa also used amphibian's hemoglobin-binding proteins. Contrary what reported a study using pathogenic Escherichia coli, haptoglobin failed exhibit bacteriostatic influence when hemoglobin. In our study, more removed by bacteria haptoglobin-hemoglobin complex than hemoglobin-plasma protein complexes stripped at similar rates extents both bacterial species.