Osmolytes and membrane lipids in adaptive response of thermophilic fungus Rhizomucor miehei to cold, osmotic and oxidative shocks

摘要: In contrast to mesophiles, in which levels of trehalose and phosphatidic acids (PA) increased only under heat shock (HS), thermophiles PA were predominant optimal growth conditions. To study the role protection adaptation various stressors, composition osmolytes membrane lipids thermophilic fungus Rhizomucor miehei was studied cold (CS), osmotic (OS) oxidative (OxS) shocks. CS resulted no accumulation glycerol mycelium, while amount decreased. The main lipid changes increase proportion with simultaneous decrease sterols (St), unsaturation degree polar ergosterol total St. OS did not cause composition, but led too. Despite low ability Mucorales produce polyols, level arabitol observed OS. OxS had effect on composition. Thus, our results show similarity difference (CS OxS) between mechanisms mesophiles.