Natural or Synthetic Therapeutics That Block PAKs

摘要: Since the late 1990s, a variety of evidence has accumulated that clearly indicates deregulation PAK1 is responsible for life-threatening diseases and disorders such as cancers. In other words, blockers, either synthetic compounds or natural products, could cure delay these PAK1-dependent disorders. turn this century, blockers have been identified developed, at least few them are already available on market be useful treatment Here we shall introduce several FK228 propolis, which help both clinicians patients who suffer from The major difference conventional chemotherapeutics (chemos) DNA/RNA/microtubule poisons unlike chemos, cause no side effects in patients, simply because not essential growth normal cells. Thus, would suitable even lifelong genetic neurofibromatosis (NF) tuberous sclerosis (TSC), addition to relatively short-term solid tumors gliomas pancreatic, colon, lung