The life and times of ivermectin — a success story

作者: Satoshi Õmura , Andy Crump

DOI: 10.1038/NRMICRO1048

关键词:

摘要: Since its introduction more than 20 years ago, ivermectin has proved to be one of the most successful therapeutic drugs in veterinary medicine, as well as the basis of one of the most …

参考文章(51)
Hugh R. Taylor, Bruce M. Greene, The status of ivermectin in the treatment of human onchocerciasis. American Journal of Tropical Medicine and Hygiene. ,vol. 41, pp. 460- 466 ,(1989) , 10.4269/AJTMH.1989.41.460
Brian O. L. Duke, Guillermo Zea-Flores, Beatriz Muñoz, Eddie W. Cupp, Julio Castro, Effects of multiple monthly doses of ivermectin on adult Onchocerca volvulus. American Journal of Tropical Medicine and Hygiene. ,vol. 43, pp. 657- 664 ,(1990) , 10.4269/AJTMH.1990.43.657
M.S.G Kwa, M.N Okoli, H Schulz-Key, P.O Okongkwo, M.H Roos, Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulus International Journal for Parasitology. ,vol. 28, pp. 1235- 1240 ,(1998) , 10.1016/S0020-7519(98)00071-X
Haruo Ikeda, Jun Ishikawa, Akiharu Hanamoto, Mayumi Shinose, Hisashi Kikuchi, Tadayoshi Shiba, Yoshiyuki Sakaki, Masahira Hattori, Satoshi Ōmura, Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis Nature Biotechnology. ,vol. 21, pp. 526- 531 ,(2003) , 10.1038/NBT820
Ivermectin and abamectin. Springer-Verlag New York Inc.. ,(1989) , 10.1007/978-1-4612-3626-9
F. M. Keita, G. De Sole, J. Giese, K. Y. Dadzie, S. Accorsi, J. Remme, O. Ba, M. Karam, E. S. Alley, K. Awadzi, Adverse reactions after large-scale treatment of onchocerciasis with ivermectin: combined results from eight community trials. Bulletin of The World Health Organization. ,vol. 67, pp. 707- 719 ,(1989)
G. J. van Oortmarssen, A. P. Plaisier, G. de Sole, J. D. F. Habbema, E. S. Alley, K. Y. Dadzie, R. H. A. Baker, J. Remme, E. M. Samba, Large scale ivermectin distribution and its epidemiological consequences. Acta Leidensia. ,vol. 59, pp. 177- 191 ,(1990)
R. W. Burg, E. O. Stapley, Isolation and Characterization of the Producing Organism Ivermectin and abamectin.. pp. 24- 32 ,(1989) , 10.1007/978-1-4612-3626-9_2