Carbapenem-resistant Acinetobacter and role of curtains in an outbreak in intensive care units.

作者: I. Das , P. Lambert , D. Hill , M. Noy , J. Bion

DOI: 10.1053/JHIN.2001.1127

关键词:

摘要: Multiple-antibiotic-resistant Acinetobacter baumanii, including meropenem resistance, was first isolated from a patient in the general intensive care unit of tertiary-referral university teaching hospital Birmingham December 1998. Similar strains were subsequently 12 other patients, those on another within hospital. The outbreak followed an increase use both units. Environmental screening revealed presence multiple-resistant species fomite surfaces and bed linen. major source appeared to be curtains surrounding patients' beds. Typing by pulsed field gel electrophoresis demonstrated that isolates environment indistinguishable. Rigorous infection control measures increased frequency cleaning with hypochlorite (1000 ppm) twice-weekly changing implemented, along restriction Isolation spp. diminished it not detected over follow-up period 18 months. To our knowledge, this is reported carbapenem-resistant UK. This also highlights environmental sources, particularly dry fabrics such as curtains, important reservoir for dissemination acinetobacters.

参考文章(19)
C Wendt, B Dietze, E Dietz, H Rüden, Survival of Acinetobacter baumannii on dry surfaces. Journal of Clinical Microbiology. ,vol. 35, pp. 1394- 1397 ,(1997) , 10.1128/JCM.35.6.1394-1397.1997
Gerald L. Mandell, R. Gordon Douglas, John E. Bennett, Principles and Practice of Infectious Diseases ,(1985)
J Tankovic, P Legrand, G De Gatines, V Chemineau, C Brun-Buisson, J Duval, Characterization of a hospital outbreak of imipenem-resistant Acinetobacter baumannii by phenotypic and genotypic typing methods. Journal of Clinical Microbiology. ,vol. 32, pp. 2677- 2681 ,(1994) , 10.1128/JCM.32.11.2677-2681.1994
James E. Peacock, LuAnne Sorrell, Frank D. Sottile, Loraine E. Price, William A. Rutala, Nosocomial respiratory tract colonization and infection with aminoglycoside-resistant Acinetobacter calcoaceticus var anitratus: epidemiologic characteristics and clinical significance. Infection Control and Hospital Epidemiology. ,vol. 9, pp. 302- 308 ,(1988) , 10.1086/645859
E.S Go, C Urban, J Burns, N Mariano, K Mosinka-Snipas, J.J Rahal, B Kreiswirth, W Eisner, Clinical and molecular epidemiology of acinetobacter infections sensitive only to polymyxin B and sulbactam The Lancet. ,vol. 344, pp. 1329- 1332 ,(1994) , 10.1016/S0140-6736(94)90694-7
Alan I. Hartstein, Abdel L. Rashad, Janice M. Liebler, Luis A. Actis, Joan Freeman, J. William Rourke, Thomas B. Stibolt, Marcelo E. Tolmasky, Gene R. Ellis, Jorge H. Crosa, Multiple intensive care unit outbreak of Acinetobacter calcoaceticus subspecies anitratus respiratory infection and colonization associated with contaminated, reusable ventilator circuits and resuscitation bags. The American Journal of Medicine. ,vol. 85, pp. 624- 631 ,(1988) , 10.1016/S0002-9343(88)80233-X
Karen D. Allen, Helen T. Green, Hospital outbreak of multi-resistant Acinetobacter anitratus: an airborne mode of spread? Journal of Hospital Infection. ,vol. 9, pp. 110- 119 ,(1987) , 10.1016/0195-6701(87)90048-X
Jean-Louis Vincent, David J Bihari, Peter M Suter, Hajo A Bruining, Jane White, Marie-Helene Nicolas-Chanoin, Michel Wolff, Robert C Spencer, Margaret Hemmer, The Prevalence of Nosocomial Infection in Intensive Care Units in Europe: Results of the European Prevalence of Infection in Intensive Care (EPIC) Study JAMA. ,vol. 274, pp. 639- 644 ,(1995) , 10.1001/JAMA.1995.03530080055041
C. Cefai, J. Richards, F.K. Gould, P. McPeake, An outbreak of Acinetobacter respiratory tract infection resulting from incomplete disinfection of ventilatory equipment Journal of Hospital Infection. ,vol. 15, pp. 177- 182 ,(1990) , 10.1016/0195-6701(90)90128-B
O. Lortholary, J.-Y. Fagon, A. B. Hoi, M. A. Slama, J. Pierre, P. Giral, R. Rosenzweig, L. Gutmann, M. Safar, J. Acar, Nosocomial Acquisition of Multiresistant Acinetobacter baumannii: Risk Factors and Prognosis Clinical Infectious Diseases. ,vol. 20, pp. 790- 796 ,(1995) , 10.1093/CLINIDS/20.4.790