Increased levels of circulating platelet-derived microparticles are associated with metastatic cutaneous melanoma.
作者： Joséphine Moreau , Fabien Pelletier , Sabeha Biichle , Guillaume Mourey , Marc Puyraveau
DOI: 10.1111/EXD.13339
关键词:
摘要: We investigated the plasma levels of PMPs in patients with 45 stage III and IV melanoma. were characterised by flow cytometry their thrombogenic activity. also link between circulating tumor burden. The significantly higher (8500 μL-1 ) than (2041 μL-1 melanoma (P=.0001). calculated a highly specific (93.3%) predictive (91.7%) cut-off value (5311 μL-1 allowing distinction high-risk metastatic activity was (clotting time: 40.7 second vs 65 second, P=.0001). There no significant association radiological tumoral syndrome level PMPs. Our data suggest role progression
sci-hub.se 参考文章(8)
Claire Laresche, Fabien Pelletier, Francine Garnache-Ottou, Thomas Lihoreau, Sabeha Biichlé, Guillaume Mourey, Philippe Saas, Philippe Humbert, Estelle Seilles, François Aubin, Increased Levels of Circulating Microparticles Are Associated with Increased Procoagulant Activity in Patients with Cutaneous Malignant Melanoma Journal of Investigative Dermatology. ,vol. 134, pp. 176- 182 ,(2014) , 10.1038/JID.2013.288
Paolo Prandoni, Anna Falanga, Andrea Piccioli, Cancer and venous thromboembolism Lancet Oncology. ,vol. 6, pp. 401- 410 ,(2005) , 10.1016/S1470-2045(05)70207-2
Shosaku Nomura, Maiko Niki, Tohru Nisizawa, Takeshi Tamaki, Michiomi Shimizu, Microparticles as Biomarkers of Blood Coagulation in Cancer Biomarkers in Cancer. ,vol. 2015, pp. 51- 56 ,(2015) , 10.4137/BIC.S30347
Donatello Castellana, Florence Toti, Jean-Marie Freyssinet, Membrane microvesicles: Macromessengers in cancer disease and progression Thrombosis Research. ,vol. 125, pp. S84- S88 ,(2010) , 10.1016/S0049-3848(10)70021-9
Hadi Goubran, Waleed Sabry, Rami Kotb, Jerard Seghatchian, Thierry Burnouf, Platelet microparticles and cancer: An intimate cross-talk. Transfusion and Apheresis Science. ,vol. 53, pp. 168- 172 ,(2015) , 10.1016/J.TRANSCI.2015.10.014
Julia Barbara Kral, Waltraud Cornelia Schrottmaier, Manuel Salzmann, Alice Assinger, Platelet Interaction with Innate Immune Cells Transfusion Medicine and Hemotherapy. ,vol. 43, pp. 78- 88 ,(2016) , 10.1159/000444807
H. Shaker, A.S. Rothmeier, C.C. Kirwan, W. Ruf, OC-09 - Microparticle-mediated transfer of TF hypercoagulability between cancer cells Thrombosis Research. ,vol. 140, ,(2016) , 10.1016/S0049-3848(16)30126-8
Arnulf Willms, Clara Müller, Henrike Julich, Niklas Klein, Robert Schwab, Christoph Güsgen, Ines Richardsen, Sebastian Schaaf, Marcin Krawczyk, Marek Krawczyk, Frank Lammert, Detlef Schuppan, Veronika Lukacs-Kornek, Miroslaw Kornek, Tumour-associated circulating microparticles: A novel liquid biopsy tool for screening and therapy monitoring of colorectal carcinoma and other epithelial neoplasia Oncotarget. ,vol. 7, pp. 30867- 30875 ,(2016) , 10.18632/ONCOTARGET.9018