作者: I. A. Cristea , F. Naudet
DOI: 10.1017/S2045796017000750
关键词:
摘要: Aims Leucht et al. in 2012 described an overview of meta-analyses the efficacy medication psychiatry and general medicine, concluding that psychiatric drugs were not less efficacious than other drugs. Our goal was to explore dissemination this highly cited paper, which combined a thought provoking message with series caveats. Methods We conducted prospectively registered citation content analysis. All papers published before June 1st citing target paper independently rated by two investigators. The primary outcome coded dichotomously whether used justify small or modest effect observed for given treatment. Secondary outcomes regarded mentioning any caveats when point making (treatment effectiveness closely resembles others), type condition (psychiatric, medical both), specific disease, treatment category type. also extracted information about financial conflict interest (COI) declared industry support. analysis descriptive tabulating variables, numbers percentages where appropriate. Co-authorship networks constructed identify possible clusters authors. An exploratory univariate logistic regression relationship between each subset pre-specified secondary outcome. Results identified 135 records retrieved analysed 120. Sixty-three (53%) quoted al.'s therapy, 113 (94%) did mention Seventy-two (60%) claim medicine; 110 (91%) conditions. Forty-one (34%) it without pointing towards category, 28 (23%) antidepressants, 18 (15%) antipsychotics. Forty (33%) included data. COIs reported 55 (46%). Univariate multivariate regressions showed association quote justifying effects medicine. Conclusions evaluation revealed overwhelmingly uncritical reception seemed indicate beyond defending as discipline, served lend support credibility therapeutic myth: trivial mental health interventions, most often drugs, are be expected therefore accepted.Protocol registration: https://osf.io/9dqat/.