Effects of irradiation on mixed müllerian tumors of the uterus

摘要: A retrospective study of 54 patients with histologically proven malignant mixed mullerian tumors the uterus was undertaken main emphasis on evaluation effects irradiation pelvic tumor control. The were staged according to FIGO classification for endometrial carcinoma and 24 classified as Stage I, 10 II, 13 III seven IV. Patients I II treated surgery alone (9 patients, three surviving) or preoperative intracavitary (13 eight combination external (12 six surviving). Five IV alone, two a 11 radiation alone. None these survived. In showing no residual in uterine specimen after irradiation, failures noted, whereas 17 (41.2%) developed recurrences. out recurred pelvis only (17%) receiving However, failed pelvis. Correlation doses given lymph nodes indicate that below 5000 rads significantly higher number recurrences take place, are uncommon over 6000 rads. difference between dosage levels is not, however, statistically significant. It suggested should be total hysterectomy bilateral salpingo-oophorectomy. more advanced disease have extremely poor prognosis therapy This has high propensity spread through lymphatics hematogenous metastases seen approximately 75% patients. Because this dissemination, significant improvements survival rate will not until effective cytotoxic agents available.