作者: Allan J. Walkey , Renda Soylemez Wiener
DOI: 10.1016/J.JCRC.2011.06.015
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摘要: Abstract Purpose We assessed factors associated with underuse of lung-protective ventilation (LPV) in patients acute lung injury (ALI). Methods A secondary analysis Acute Respiratory Distress Syndrome Clinical Trials Network trial data, 1999 to 2005, was conducted. Tidal volumes recorded before randomization were analyzed determine receipt LPV (tidal volume ≤6.5 mL/kg predicted body weight [PBW]). Results Of 1385 participants, 430 (31.2%) received LPV. Average tidal 7.65 ± 1.82 PBW; measured greater than "lung-protective" by 6.5 PBW (mean difference, 67 108 mL; P Conclusions Simple interventions could substantially improve adherence among ALI and warrant prospective study.