Serologically detected "new" tick-borne zoonoses in eastern Croatia.

摘要: Methods. Seroepidemiologic testing was performed in 102 subjects with a history of tick bite, who either requested examination for bite or were suspected having tick-borne disease. The study carried out during the 1998-1999 period area Vukovar-Srijem, Osijek-Baranya, and Brod-Posavina counties. Serum analysis by indirect immunofluorescence assay detection antibodies to causative agents human monocytic granulocytic ehrlichiosis (Ehrlichia chaffeensis agent), babesiosis (Babesia divergens), rickettsiosis. Enzyme-linked immunosorbent used spirochete Borrelia burgdorferi, cause Lyme assays at Department Microbiology, Osijek Public Health Institute Osijek, their results confirmed Microbiology Immunology, School Medicine Ljubljana, Slovenia. Results. Ehrlichia chaffensis detected 5 sera, agent 7 sera. A low titer etiologic microti )w as only single serum. Eight sera that positive rickettsial contained rather high titers against Rickettsia conorii, Mediterranean fever, rickettsii, Rocky Mountain spotted fever. In six these 8 typhi, murine typhus, possibly cross-reaction some “newly detected” rickettsia circulating this part Europe, most likely slovaca. Positive burgdorferi 15 Conclusion. newly rickettsiae indirectly demonstrated circulate eastern parts Croatia. obtained IFA failed provide definite evidence circulation agent, because our Babesia microti, which prevails USA, but not divergens, is predominant disease Europe. Serologic infection 80% skin manifestation