Existing and Emerging Technologies for Tumor Genomic Profiling

摘要: Ongoing global genome characterization efforts are revolutionizing our knowledge of cancer genomics and tumor biology. In parallel, information gleaned from these studies on driver gene alterations—mutations, copy number alterations, translocations, and/or chromosomal rearrangements—can be leveraged, in principle, to develop a cohesive framework for individualized treatment. These possibilities have been enabled, large degree, by revolutionary advances genomic technologies that facilitate systematic profiling hallmark genetic alterations at increasingly fine resolutions. innovations existing technologies, as well the many emerging will likely continue advance translational precision medicine.