Nanoemulsion W805EC improves immune responses upon intranasal delivery of an inactivated pandemic H1N1 influenza vaccine

作者: Subash C. Das , Masato Hatta , Peter R. Wilker , Andrzej Myc , Tarek Hamouda

DOI: 10.1016/J.VACCINE.2012.09.007

关键词:

摘要: Currently available influenza vaccines provide suboptimal protection. In order to improve the quality of protective immune responses elicited following vaccination, we developed an oil-…

参考文章(38)
Shin-ichi Tamura, Hirono Funato, Yoshihiro Hirabayashi, Kiyoshi Kikuta, Yujiro Suzuki, Takashi Nagamine, Chikara Aizawa, Masaro Nakagawa, Takeshi Kurata, Functional role of respiratory tract haemagglutinin-specific IgA antibodies in protection against influenza Vaccine. ,vol. 8, pp. 479- 485 ,(1990) , 10.1016/0264-410X(90)90250-P
Michael A. Riddiough, Influenza Vaccination JAMA. ,vol. 249, pp. 3189- 3195 ,(1983) , 10.1001/JAMA.1983.03330470029026
L.R. Stanberry, J.K. Simon, C. Johnson, P.L. Robinson, J. Morry, M.R. Flack, S. Gracon, A. Myc, T. Hamouda, J.R. Baker, Safety and immunogenicity of a novel nanoemulsion mucosal adjuvant W805EC combined with approved seasonal influenza antigens. Vaccine. ,vol. 30, pp. 307- 316 ,(2012) , 10.1016/J.VACCINE.2011.10.094
Tarek Hamouda, Alexander Chepurnov, Nicholas Mank, Jessica Knowlton, Tatiana Chepurnova, Andrzej Myc, Joyce Sutcliffe, James Baker, Jr, Efficacy, immunogenicity and stability of a novel intranasal Nanoemulsion-adjuvanted influenza vaccine in a murine model Human Vaccines. ,vol. 6, pp. 585- 594 ,(2010) , 10.4161/HV.6.7.11818
Tarek Hamouda, Andrzej Myc, Brian Donovan, Amy Y. Shih, Jon D. Reuter, James R. Baker, A novel surfactant nanoemulsion with a unique non-irritant topical antimicrobial activity against bacteria, enveloped viruses and fungi Microbiological Research. ,vol. 156, pp. 1- 7 ,(2001) , 10.1078/0944-5013-00069
S. B Mossad, Demystifying FluMist, a new intranasal, live influenza vaccine. Cleveland Clinic Journal of Medicine. ,vol. 70, pp. 801- 806 ,(2003) , 10.3949/CCJM.70.9.801
Peter Palese, Adolfo García-Sastre, None, Influenza vaccines: present and future Journal of Clinical Investigation. ,vol. 110, pp. 9- 13 ,(2002) , 10.1172/JCI15999
Yasushi Itoh, Kyoko Shinya, Maki Kiso, Tokiko Watanabe, Yoshihiro Sakoda, Masato Hatta, Yukiko Muramoto, Daisuke Tamura, Yuko Sakai-Tagawa, Takeshi Noda, Saori Sakabe, Masaki Imai, Yasuko Hatta, Shinji Watanabe, Chengjun Li, Shinya Yamada, Ken Fujii, Shin Murakami, Hirotaka Imai, Satoshi Kakugawa, Mutsumi Ito, Ryo Takano, Kiyoko Iwatsuki-Horimoto, Masayuki Shimojima, Taisuke Horimoto, Hideo Goto, Kei Takahashi, Akiko Makino, Hirohito Ishigaki, Misako Nakayama, Masatoshi Okamatsu, Kazuo Takahashi, David Warshauer, Peter A. Shult, Reiko Saito, Hiroshi Suzuki, Yousuke Furuta, Makoto Yamashita, Keiko Mitamura, Kunio Nakano, Morio Nakamura, Rebecca Brockman-Schneider, Hiroshi Mitamura, Masahiko Yamazaki, Norio Sugaya, M. Suresh, Makoto Ozawa, Gabriele Neumann, James Gern, Hiroshi Kida, Kazumasa Ogasawara, Yoshihiro Kawaoka, In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses Nature. ,vol. 460, pp. 1021- 1025 ,(2009) , 10.1038/NATURE08260
T Jefferson, D Rivetti, A Rivetti, M Rudin, C Di Pietrantonj, V Demicheli, Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review The Lancet. ,vol. 366, pp. 1165- 1174 ,(2005) , 10.1016/S0140-6736(05)67339-4
K. M. Edwards, W. D. Dupont, M. K. Westrich, W. D. Plummer, P. S. Palmer, P. F. Wright, A Randomized Controlled Trial of Cold-Adapted and Inactivated Vaccines for the Prevention of Influenza A Disease The Journal of Infectious Diseases. ,vol. 169, pp. 68- 76 ,(1994) , 10.1093/INFDIS/169.1.68