Radical surgery for hilar cholangiocarcinoma.

作者: S. Jonas , C. Benckert , A. Thelen , E. Lopez-Hänninen , T. Rösch

DOI: 10.1016/J.EJSO.2007.09.024

关键词:

摘要: In the therapy of hilar cholangiocarcinoma, most favorable survival rates over long-term are achieved by a surgical concept involving no-touch-technique, en-bloc-resection and wide tumor-free margins. Currently, these goals can be best our strategy to combine extended right hepatic resections principle portal vein resection. spite extending resectability patients with locally advanced tumors, formally curative could performed in 80% patients. The 5-year rate is 61%. Liver transplantation had been abandoned centers 1980s due poor overall results. Recently, neoadjuvant radiochemotherapy has reported result excellent figures at least subset suffering from cholangiocellular carcinoma arising primary sclerosing cholangitis (PSC). This protocol mainly proposed Mayo Clinic group reached those whom it applicable. A substantial drop out this regimen tumor progression or treatment related complications still problem.

参考文章(34)
Hideki Nishio, Ernest Hidalgo, Zaed Z. R. Hamady, Kadiyala V Ravindra, Anil Kotru, Dowmitra Dasgupta, Ahmed Al-Mukhtar, K Rajendra Prasad, Giles J. Toogood, J Peter A. Lodge, Left hepatic trisectionectomy for hepatobiliary malignancy: results and an appraisal of its current role. Annals of Surgery. ,vol. 242, pp. 267- 275 ,(2005) , 10.1097/01.SLA.0000171304.70678.11
Julie K. Heimbach, Gregory J. Gores, David M. Nagorney, Charles B. Rosen, Liver transplantation for perihilar cholangiocarcinoma after aggressive neoadjuvant therapy: a new paradigm for liver and biliary malignancies? Surgery. ,vol. 140, pp. 331- 334 ,(2006) , 10.1016/J.SURG.2006.01.010
Henri Bismuth, Surgical anatomy and anatomical surgery of the liver World Journal of Surgery. ,vol. 6, pp. 3- 9 ,(1982) , 10.1007/BF01656368
Michael F. Gerhards, Thomas M. van Gulik, Laurens Th. de Wit, Hugo Obertop, Dirk J. Gouma, Evaluation of morbidity and mortality after resection for hilar cholangiocarcinoma—a single center experience☆ Surgery. ,vol. 127, pp. 395- 404 ,(2000) , 10.1067/MSY.2000.104250
Sven Jonas, Jens Mittler, Andreas Pascher, Tom Theruvath, Armin Thelen, Jochen Klupp, Jan M. Langrehr, Peter Neuhaus, Extended indications in living-donor liver transplantation: bile duct cancer. Transplantation. ,vol. 80, ,(2005) , 10.1097/01.TP.0000187106.29908.2B
S. Jonas, Th. Steinmüller, P. Neuhaus, Chirurgische Therapie von Leberhilustumoren Chirurg. ,vol. 72, pp. 775- 783 ,(2001) , 10.1007/S001040170105
Tomoki Ebata, Masato Nagino, Junichi Kamiya, Katsuhiko Uesaka, Tetsuro Nagasaka, Yuji Nimura, Hepatectomy with portal vein resection for hilar cholangiocarcinoma: audit of 52 consecutive cases. Annals of Surgery. ,vol. 238, pp. 720- 727 ,(2003) , 10.1097/01.SLA.0000094437.68038.A3
Rainer Eckhard Hintze, Hassan Abou-Rebyeh, Andreas Adler, Wilfried Veltzke-Schlieker, Roland Felix, Bertram Wiedenmann, Magnetic resonance cholangiopancreatography-guided unilateral endoscopic stent placement for Klatskin tumors. Gastrointestinal Endoscopy. ,vol. 53, pp. 40- 46 ,(2001) , 10.1067/MGE.2001.111388
Yuichiro Tojima, Masato Nagino, Tomoki Ebata, Katsuhiko Uesaka, Junichi Kamiya, Yuji Nimura, Immunohistochemically Demonstrated Lymph Node Micrometastasis and Prognosis in Patients With Otherwise Node-Negative Hilar Cholangiocarcinoma Annals of Surgery. ,vol. 237, pp. 201- 207 ,(2003) , 10.1097/01.SLA.0000048446.18118.FC
K. Weinbren, S. S. Mutum, Pathological aspects of cholangiocarcinoma The Journal of Pathology. ,vol. 139, pp. 217- 238 ,(1983) , 10.1002/PATH.1711390210