Epidermal Growth Factor and a New Derivative

作者: C. Richard Savage , Stanley Cohen

DOI: 10.1016/S0021-9258(19)44568-7

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摘要: A new procedure has been devised for the preparation of pure epidermal growth factor in high yield. The method involves a two-step column fractionation crude extracts submaxillary gland obtained from adult male mice. Biologically active lacking COOH-terminal Leu-Arg residues was also isolated.

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C. Richard Savage, Stanley Cohen, Epidermal Growth Factor and a New Derivative Journal of Biological Chemistry. ,vol. 247, pp. 7609- 7611 ,(1972) , 10.1016/S0021-9258(19)44568-7