Vitamin D Status and Its Associations with Disease Activity and Severity in African Americans with Recent-onset Rheumatoid Arthritis

摘要: Objective. To examine the prevalence of vitamin D insufficiency and associations concentration with disease status in African Americans rheumatoid arthritis (RA). Methods. Study participants (n = 266) were enrolled Consortium for Longitudinal Evaluation Early RA (CLEAR) Registry. The 25(OH)-D was measured on baseline plasma, (baseline at 3 years’ duration) examined using univariate multivariate regression. Results. (≤ 37.5 nmol/l or 15 ng/ml) 50%, highest winter. In unadjusted analyses, concentrations inversely associated pain (p 0.04), swollen joints Disease Activity Score (DAS28, p 0.05) but not measures duration. There no any years, exception a positive borderline association factor positivity enrollment 0.05). Conclusion. Vitamin is common recent-onset RA. Unadjusted circulating pain, joints, DAS28 explained by differences season, age, gender significant analyses. contrast to reports Northern Europeans early inflammatory arthritis, there are strong symptoms severity