Selection of twenty-four highly informative SNP markers for human identification and paternity analysis in Koreans

摘要: A number of DNA marker types suitable for human identification and parentage testing have been developed, which single nucleotide polymorphisms (SNPs) merit attention as they are abundant, genetically stable, amenable to high-throughput automated analysis. In this regard, 24 highly informative SNP markers representing each 22 autosome both sex chromosomes were selected, the allele genotype frequencies these SNPs determined in a group composed 30 unrelated Koreans. Based on frequency data from group, estimated probability identity (PI) paternity exclusion (PE) with autosomal loci 1.905 × 10−10 98.9%, respectively. The study offer small but accurate database that will be an essential reference SNP-based forensic application future.