Current Status of Colorectal Cancer Therapy

摘要: In 2004, the American Cancer Society estimated that approx 150,000 new cases of colorectal cancer would occur in United States and more than 57,000 Americans die disease, making it second most common cause cancer-related death (1). Despite improvements screening techniques, 30–40% patients with present locoregionally advanced or metastatic disease are not candidates for potentially curative therapy. Overall, progress surgical neoadjuvant/adjuvant management locally confined has been rapid very encouraging over past several years. addition, median survival improved almost fourfold, as active salvage systemic agents have emerged rapidly integrated into first-line regimens.