Avian IgY antibodies: characteristics and applications in immunodiagnostic

作者: Lívia Silveira Munhoz , Gilberto D'Ávila Vargas , Geferson Fischer , Marcelo de Lima , Paulo Augusto Esteves

DOI: 10.1590/S0103-84782014000100025

关键词:

摘要: Immunoglobulin Y (IgY) is the major antibody isotype in birds, reptiles, amphibia, and lungfish, playing a similar biological role as mammal IgG. Due to its phylogenetic distance, immune diversification presence egg yolk, IgY provide number of advantages immunodiagnostic compared IgG from mammals. Moreover, production agreement with international efforts reduce, refine if possible, replace animals experimentation, contributing substantially favor animal welfare. This article presents an overview about structural functional features, applications immunodiagnostic, well chicken antibodies use.

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