Impact of high-sensitivity c-reactive protein on predicting long-term mortality of acute myocardial infarction

摘要: Although the C-reactive protein (CRP) concentration measured shortly after acute myocardial infarction (AMI) is associated with infarct size, its prognostic value controversial. The reduction of CRP accelerated by reperfusion. Therefore, concentration, during stable phase AMI in patients treated predominantly reperfusion therapies, may be independent size and predict long-term mortality. We studied 1,309 enrolled Osaka Acute Coronary Insufficiency Study between April 1999 June 2001. was (mean 25 days onset). were followed for an average 522 days. Reperfusion therapies performed 90% patients. Patients highest quartile values (≥0.38 mg/dl) older, had higher prevalences diabetes mellitus, Killip classes than lower 3 quartiles (<0.38 mg/dl). Multivariate logistic regression analysis revealed that independently age absence revascularization therapies. a mortality rate (8.9% vs 2.0%; p <0.001). Cox predictor (hazard ratio 4.94, 95% confidence interval 1.13 to 21.6). conclude not era but significantly AMI.