Platelet-derived growth factor (PDGF)
作者： Arne Östman , Carl-Henrik Heldin
DOI: 10.1016/B0-12-475570-4/01034-9
关键词:
摘要: PDGFs are growth factors for mesenchymal cells that act through cell surface tyrosine kinase receptors. have important functions during development. A number of pathological conditions associated with overactivity PDGF
sci-hub.se 参考文章(12)
Mats Sjöquist, Carl-Henrik Heldin, Kristofer Rubin, Arne Ostman, Tobias Sjöblom, Elisabeth Buchdunger, Kristian Pietras, Inhibition of PDGF Receptor Signaling in Tumor Stroma Enhances Antitumor Effect of Chemotherapy Cancer Research. ,vol. 62, pp. 5476- 5484 ,(2002)
Peter Duchek, Kálmán Somogyi, Gáspár Jékely, Simone Beccari, Pernille Rørth, Guidance of Cell Migration by the Drosophila PDGF/VEGF Receptor Cell. ,vol. 107, pp. 17- 26 ,(2001) , 10.1016/S0092-8674(01)00502-5
Richard A Klinghoffer, Peter F Mueting-Nelsen, Alexander Faerman, Moshe Shani, Philippe Soriano, The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions. Molecular Cell. ,vol. 7, pp. 343- 354 ,(2001) , 10.1016/S1097-2765(01)00182-4
Koichi Kozaki, Wolfgang E. Kaminski, Jingjing Tang, Stan Hollenbach, Per Lindahl, Carol Sullivan, Jin-Chen Yu, Keith Abe, Paul J. Martin, Russell Ross, Christer Betsholtz, Neill A. Giese, Elaine W. Raines, Blockade of platelet-derived growth factor or its receptors transiently delays but does not prevent fibrous cap formation in ApoE null mice. American Journal of Pathology. ,vol. 161, pp. 1395- 1407 ,(2002) , 10.1016/S0002-9440(10)64415-X
Jane F. Apperley, Martine Gardembas, Junia V. Melo, Robin Russell-Jones, Barbara J. Bain, E. Joanna Baxter, Andrew Chase, Judith M. Chessells, Marie Colombat, Claire E. Dearden, Sasa Dimitrijevic, François-X. Mahon, David Marin, Zariana Nikolova, Eduardo Olavarria, Sandra Silberman, Beate Schultheis, Nicholas C.P. Cross, John M. Goldman, Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. The New England Journal of Medicine. ,vol. 347, pp. 481- 487 ,(2002) , 10.1056/NEJMOA020150
Christer Betsholtz, Linda Karlsson, Per Lindahl, Developmental roles of platelet‐derived growth factors BioEssays. ,vol. 23, pp. 494- 507 ,(2001) , 10.1002/BIES.1069
Nicole Meyer-Morse, Gabriele Bergers, Emily Bergsland, Steven Song, Douglas Hanahan, Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors Journal of Clinical Investigation. ,vol. 111, pp. 1287- 1295 ,(2003) , 10.1172/JCI17929
Maria Enge, Mattias Bjarnegård, Holger Gerhardt, Erika Gustafsson, Mattias Kalén, Noomi Asker, Hans‐Peter Hammes, Moshe Shani, Reinhardt Fässler, Christer Betsholtz, Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy The EMBO Journal. ,vol. 21, pp. 4307- 4316 ,(2002) , 10.1093/EMBOJ/CDF418
Kristian Pietras, Tobias Sjöblom, Kristofer Rubin, Carl-Henrik Heldin, Arne Östman, PDGF receptors as cancer drug targets Cancer Cell. ,vol. 3, pp. 439- 443 ,(2003) , 10.1016/S1535-6108(03)00089-8
Douglas Fambrough, Kimberly McClure, Andrius Kazlauskas, Eric S Lander, Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes. Cell. ,vol. 97, pp. 727- 741 ,(1999) , 10.1016/S0092-8674(00)80785-0